MCHPATSAMD21E16B-AZVAO

Overview

ATSAMD21E16B-AZVAO is a Microchip SAM D21 family ARM Cortex-M0+ microcontroller in a 32-pin TQFP package. It includes 64 KB of flash and USB support, making it a flexible general-purpose MCU for small embedded designs. The extended-temperature rating makes it suitable for a wider range of industrial and field applications.

Why Choose This Part

This part gives you a modern Cortex-M0+ core with a straightforward footprint and a small pin count, which helps keep board area and BOM cost down. USB support is a practical advantage for firmware update paths, device interfaces, and simple connectivity without adding a separate bridge IC. The 64 KB flash size is a useful middle ground for compact applications that still need more than the smallest entry-level MCU.

Applications

Getting Started

Microchip's MPLAB X IDE and MPLAB Harmony are the usual starting points for SAM D21 development, and GCC-based toolchains are also commonly used. For hardware, engineers typically begin with a SAM D21 Xplained Pro or a compatible third-party board before moving to a custom TQFP32 design. A Microchip-compatible debugger/programmer, such as an Atmel-ICE or other SWD-capable tool, is helpful for flashing and debug during bring-up.

Dev Boards

Development boards and breakout modules featuring the ATSAMD21E16B-AZVAO or compatible chips — ready to use for prototyping.

Seeed Studio XIAO SAMD21 Seeed Technology Co., Ltd

ATSAMD21G18 XIAO SAMD21 SAM D ARM® Cortex®-M0 MCU 32-Bit Embedded Evaluation Board

Digi-Key 509 in stock

Seeed Studio XIAO SAMD21 Seeed Technology Co., Ltd

ATSAMD21G18 XIAO SAMD21 SAM D ARM® Cortex®-M0+ MCU 32-Bit Embedded Evaluation Board

Digi-Key 3,141 in stock

Adafruit Feather M0 Express Adafruit Industries LLC

ATSAMD21G18 Feather M0 Express SAM D ARM® Cortex®-M0+ MCU 32-Bit Embedded Evaluation Board

Digi-Key Mouser 364 in stock

Arduino Nano 33 IoT Arduino

The Arduino Nano 33 IoT with Headers (ABX00032) is a compact and versatile development board featuring the ARM® Cortex®-

Digi-Key Mouser 355 in stock

Arduino Nano 33 IoT Arduino

The Arduino Nano 33 IoT (ABX00027) is an advanced evaluation platform designed for IoT applications, featuring the 32 bi

Digi-Key Mouser 657 in stock

SAMD21E Family

Comparing specs that differ across variants. The current part is highlighted.

Also Consider

ATSAMD21G18A-AU MCHPMicrochip Technology - A closely related SAM D21 variant with more flash and a very common package choice for similar USB-capable embedded designs.

ATSAMD21E18A-AU MCHPMicrochip Technology - Same family and small-package form factor, with a higher-memory option if the application needs more firmware space.

STM32F072C8T6 STMicroelectronics - A comparable Cortex-M0 USB-capable microcontroller for compact designs where an STM32 ecosystem is preferred.